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Human papillomavirus (HPV) vaccine education

Health Factors: Sexual Activity
Decision Makers: Healthcare Professionals & Advocates Public Health Professionals & Advocates
Evidence Rating: Insufficient Evidence
Population Reach: 10-19% of WI's population
Impact on Disparities: No impact on disparities likely

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Educational efforts inform young women and men about HPV and its consequences as well as the benefits of vaccinating against the disease. Education may be provided in person, by telephone, in writing, or by other media such as videos. HPV vaccines protect against HPV and cervical cancer; one additionally protects against genital warts. Vaccines are most effective in individuals who receive a full course (3 doses) and have no previous HPV (Medeiros 2009, Rambout 2007).

Expected Beneficial Outcomes

Increased vaccination
Increased HIV and STI knowledge
Reduced incidence of HPV

Evidence of Effectiveness

There is insufficient evidence to determine whether educational efforts increase HPV vaccination rates among eligible adolescent girls and young women (Gerend 2013), though greater vaccine-related knowledge is associated with higher uptake (Kessels 2012). Available evidence indicates that educational interventions may increase HPV knowledge and vaccination intentions among both young women (Gerend 2013, Krawczyk 2012, Kester 2014) and men (Krawczyk 2012), including black men and women (Kester 2014), and that tailoring the intervention to a specific audience may strengthen effects (Gerend 2013). Provider recommendation of the vaccine increases acceptability (Brewer 2007) and uptake (Kester 2013, Kessels 2012). Additional evidence is needed to confirm effects.

There is no evidence that receipt of the HPV vaccine increases sexual risk behavior among adolescent girls and young women (Mayhew 2014, Rysavy 2014).

Implementation Resources

CDC-HPV professional resources - Centers for Disease Control and Prevention (CDC). Professional resources: Resources for health professionals. Accessed on January 11, 2016

Citations - Description

Medeiros 2009* - Medeiros LR, Rosa DD, da Rosa MI, Bozzetti MC, Zanini RR. Efficacy of human papillomavirus vaccines: A systematic quantitative review. International Journal of Gynecological Cancer. 2009;19(7):1166-76. Accessed on March 1, 2016
Rambout 2007 - Rambout L, Hopkins L, Hutton B, Fergusson D. Prophylactic vaccination against human papillomavirus infection and disease in women: A systematic review of randomized controlled trials. Canadian Medical Association Journal. 2007;177(5):469-79. Accessed on May 24, 2016

Citations - Evidence

Brewer 2007* - Brewer NT, Fazekas KI. Predictors of HPV vaccine acceptability: A theory-informed, systematic review. Preventive Medicine. 2007;45(2-3):107-14. Accessed on May 20, 2016
Gerend 2013* - Gerend MA, Shepherd MA, Lustria MLA. Increasing human papillomavirus vaccine acceptability by tailoring messages to young adult women’s perceived barriers. Sexually Transmitted Diseases. 2013;40(5):401–5. Accessed on January 14, 2016
Kessels 2012* - Kessels SJ, Marshall HS, Watson M, et al. Factors associated with HPV vaccine uptake in teenage girls: A systematic review. Vaccine. 2012;30(24):3546–56. Accessed on December 22, 2015
Kester 2013 - Kester LM, Zimet GD, Fortenberry JD, Kahn JA, Shew ML. A national study of HPV vaccination of adolescent girls: Rates, predictors, and reasons for non-vaccination. National Institutes of Health Public Access (NIH). 2014;17(5):879-885. Accessed on May 20, 2016
Kester 2014* - Kester LM, Shedd-Steele RB, Dotson-Roberts CA, Smith J, Zimet GD. The effects of a brief educational intervention on human papillomavirus knowledge and intention to initiate HPV vaccination in 18-26 year old young adults. Gynecologic Oncology. 2014;132(Suppl 1):S9–12. Accessed on December 30, 2015
Krawczyk 2012* - Krawczyk A, Lau E, Perez S, et al. How to inform: Comparing written and video education interventions to increase human papillomavirus knowledge and vaccination intentions in young adults. Journal of American College Health. 2012;60(4):316–22. Accessed on January 12, 2016
Mayhew 2014* - Mayhew A, Mullins TLK, Ding L, et al. Risk perceptions and subsequent sexual behaviors after HPV vaccination in adolescents. Pediatrics. 2014;133(3):404–11. Accessed on December 15, 2015
Rysavy 2014* - Rysavy MB, Kresowik JD, Liu D, et al. Human papillomavirus vaccination and sexual behavior in young women. Journal of Pediatric and Adolescent Gynecology. 2014;27(2):67–71. Accessed on January 14, 2016

Page Last Updated

October 24, 2014

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